Whilst previous observational studies have linked negative thought processes such as an external locus of control and holding negative cognitive styles with depression, the directionality of these associations and the potential role that these factors play in the transition to adulthood and parenthood has not yet been investigated. This study examined the association between locus of control and negative cognitive styles in adolescence and probable depression in young adulthood and whether parenthood moderated these associations. Using a UK prospective population-based birth (...) cohort study: the Avon Longitudinal Study of Parents and Children, we examined the association between external locus of control and negative cognitive styles in adolescence with odds of depression in 4,301 young adults using logistic regression models unadjusted and adjusted for potential confounding factors. Interaction terms were employed to examine whether parenthood moderated these associations. Over 20% of young adults in our sample were at or above the clinical threshold indicating probable depression. For each standard deviation increase in external locus of control in adolescence, there was a 19% higher odds of having probable depression in young adulthood, after adjusting for various confounding factors including baseline mood and different demographic and life events variables. Similarly, for each SD increase in negative cognitive styles in adolescence, there was a 29% higher odds of having probable depression in the adjusted model. We found little evidence that parenthood status moderated the relationship between external locus of control or negative cognitive styles in adolescence and probable depression following adjustment for confounding factors. Effect estimates were comparable when performed in the complete case dataset. These findings suggest that having an external locus of control and holding negative cognitive styles in mid- to late adolescence is associated with an increased likelihood of probable depression in young adulthood. (shrink)

Performance in perceptual tasks often improves with practice. This effect is known as ‘perceptual learning,’ and it has been the source of a great deal of interest and debate over the course of the last century. Here, we consider the effects of perceptual learning within the context of signal detection theory. According to signal detection theory, the improvements that take place with perceptual learning can be due to increases in internal signal strength or decreases in internal noise. We used a (...) combination of psychophysical techniques (external noise masking and double‐pass response consistency) that involve corrupting stimuli with externally added noise to discriminate between the effects of changes in signal and noise as observers learned to identify sets of unfamiliar visual patterns. Although practice reduced thresholds by as much as a factor of 14, internal noise remained virtually fixed throughout training, indicating learning served to predominantly increase the strength of the internal signal. We further examined the specific nature of the changes that took place in signal strength by correlating the externally added noise with observer's decisions across trials (response classification). This technique allowed us to visualize some of the changes that took place in the linear templates used by the observers as learning occurred, as well as test the predictions of a linear template‐matching model. Taken together, the results of our experiments offer important new theoretical constraints on models of perceptual learning. (shrink)

Several high-profile episodes have recently thrust drug safety and the pharmaceutical industry's practices into the spotlight. Merck's recall of the drug Vioxx, for instance, was a major news event. GlaxoSmithKline's suppression of data linking suicidal behavior among children to Paxil also galvanized tremendous public attention. What differentiates these events from the usual evolving process of scientific knowledge, and marks them with an aura of “scandal,” are questions about the propriety of corporate behavior. Who knew what, and when did they know (...) it? Concerns are growing about the potential for industry sponsors to suppress negative results from clinical trials research. Scientists, medical journal editors, legislators, and the public have called for greater transparency in the conduct of clinical trials and the drug approval process. (shrink)

The concept of the receptive field, first articulated by Hartline, is central to visual neuroscience. The receptive field of a neuron encompasses the spatial and temporal properties of stimuli that activate the neuron, and, as Hubel and Wiesel conceived of it, a neuron’s receptive field is static. This makes it possible to build models of neural circuits and to build up more complex receptive fields out of simpler ones. Recent work in visual neurophysiology is providing evidence that the classical receptive (...) field is an inaccurate picture. The receptive field seems to be a dynamic feature of the neuron. In particular, the receptive field of neurons in V1 seems to be dependent on the properties of the stimulus. In this paper, we review the history of the concept of the receptive field and the problematic data. We then consider a number of possible theoretical responses to these data. (shrink)

Introduction No consent for health and medical research is appropriate when the criteria for a waiver of consent are met, yet some ethics committees and data custodians still require informed consent. Methods A single-blind parallel-group randomised controlled trial: 1129 families of children born at a South Australian hospital were sent information explaining data linkage of childhood immunisation and hospital records for vaccine safety surveillance with 4 weeks to opt in or opt out by reply form, telephone or email. A subsequent (...) telephone interview gauged the intent of 1026 parents (91%) in relation to their actions and the sociodemographic differences between participants and non-participants in each arm. Results The participation rate was 21% (n=120/564) in the opt-in arm and 96% (n=540/565) in the opt-out arm (χ2 (1 df) = 567.7, p<0.001). Participants in the opt-in arm were more likely than non-participants to be older, married/de facto, university educated and of higher socioeconomic status. Participants in the opt-out arm were similar to non-participants, except men were more likely to opt out. Substantial proportions did not receive, understand or properly consider study invitations, and opting in or opting out behaviour was often at odds with parents' stated underlying intentions. Conclusions The opt-in approach resulted in low participation and a biased sample that would render any subsequent data linkage unfeasible, while the opt-out approach achieved high participation and a representative sample. The waiver of consent afforded under current privacy regulations for data linkage studies meeting all appropriate criteria should be granted by ethics committees, and supported by data custodians. Trial registration number Australian New Zealand Clinical Trials Registry ACTRN12610000332022. (shrink)

BACKGROUND -/- The importance of ontologies in the biomedical domain is generally recognized. However, their quality is often too poor for large-scale use in critical applications, at least partially due to insufficient training of ontology developers. -/- OBJECTIVE -/- To show the efficacy of guideline-based ontology development training on the performance of ontology developers. The hypothesis was that students who received training on top-level ontologies and design patterns perform better than those who only received training in the basic principles of (...) formal ontology engineering. -/- METHODS -/- A curriculum was implemented based on a guideline for ontology design. A randomized controlled trial on the efficacy of this curriculum was performed with 24 students from bioinformatics and related fields. After joint training on the fundamentals of ontology development the students were randomly allocated to two groups. During the intervention, each group received training on different topics in ontology development. In the assessment phase, all students were asked to solve modeling problems on topics taught differentially in the intervention phase. Primary outcome was the similarity of the students’ ontology artefacts compared with gold standard ontologies developed by the authors before the experiment; secondary outcome was the intra-group similarity of group members’ ontologies. -/- RESULTS -/- The experiment showed no significant effect of the guideline-based training on the performance of ontology developers (a) the ontologies developed after specific training were only slightly but not significantly closer to the gold standard ontologies than the ontologies developed without prior specific training; (b) although significant differences for certain ontologies were detected, the intra-group similarity was not consistently influenced in one direction by the differential training. -/- CONCLUSION -/- Methodologically limited, this study cannot be interpreted as a general failure of a guideline-based approach to ontology development. Further research is needed to increase insight into whether specific development guidelines and practices in ontology design are effective. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Horace and the Dialectic of Freedom: Readings in Epistles 1Barbara K. GoldW. R. Johnson. Horace and the Dialectic of Freedom: Readings in Epistles 1. Ithaca: Cornell University Press, 1993. xiv 1 172 pp. Cloth, $27.50. (Townsend Lectures)A colleague once expressed shock that I was reading Horace’s Epistles. They are, she said, the most boring works in all of Latin literature. It seems likely that this was not an (...) idiosyncratic pronouncement: the Epistles are rarely the subjects of critical work and even less frequently taught.But now we have the second book to appear in the past decade on the first book of Horace’s Epistles. Ross Kilpatrick’s 1986 volume on The Poetry of Friendship: Horace, Epistles 1 focused closely on the theme of amicitia in these poems. Now Ralph Johnson has produced a new appreciation of Horace by tracing another theme through Horace’s letters to his friends: freedom. The book is less a critical exegesis of the Epistles than a highly personal and emotionally charged meditation on what drove Horace to write these so-called letters in the twilight of his composing years. The chapter headings indicate the unorthodox approach Johnson has chosen: “Running on Empty,” “In the Rag and Bone Shop,” “Gardens.”Johnson presents us with a Horace who is engaged in a “messy” and irresoluble dialectic with himself, his friends, and his readers. Neither Horace nor Johnson offers any comforting or banal bipolarities; Johnson cautions often against the sic et non approach whereby we, like boll weevils, bore through the haze of confusions looking for the “nugget” (Virginia Woolf’s word) behind the complexities instead of accepting the power of antinomies and their meaning for human experience (144). Johnson’s Horace is thus an ambivalent and protean creature: still a satirist, but somewhat softer now than he was in the 30s; an outsider looking in but never really a part of the hive; a man suffused with anger and resentment, yet capable of a dry and impartial skepticism and a sanguine hope about our ability to live our lives well; carnal and crazy, but mature and clear-headed; an Orphic shaman figure, who mediates between lowly humans and figures of the great (Augustus) or nature herself and delivers the truth from his lofty position, but also a poet of lowly beginnings, caught in embarrassing positions and forced to kowtow to his superiors; a man absolutely insistent on his [End Page 335] freedom and individuality yet part of a court circle of sorts; a wry picaro who nonetheless sometimes plays the role of Stoic progrediens: a naughty scarecrow in the garden, an agrarian sophist, with one foot in the city and one on his Sabine farm, trying to figure out how to be a proper gardener.But, for me, there are too many Horaces here, and they cannot all exist simultaneously. It is hard to see the spontaneous, wry picaro next to the poet who desires a return to civility and decorum or the committed city dweller who develops a love for the rural life. While it may be true that Horace changed masks when the occasion suited, his representations of himself seem to me to be fairly consistent by Ep. 1.20. The Horace I see here is more comfortable with himself than Johnson’s Horace is. He has come to terms with Maecenas, with his father, and with his life in Rome. He understands why it is necessary to avoid chasing after wealth (fuge magna, 10.32) in order to achieve the internal peace and true freedom that he seeks. But he is always a city dweller and never comfortable with his Sabine farm as more than a symbol of what the rural life could offer. (In an interesting aside, Johnson admits that he might be sentimentalizing Horace’s view of the farm: “I’m an ardent urbanite without even a window box” [150 n. 5].) Horace saw and used elements of nature throughout his poetry as evocative symbols of the place of human life in the larger natural universe, but I’m certain that he never got his hands dirty.It is, however, no wonder that so... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Feminism and Classics:Framing the Research AgendaBarbara K. GoldA landmark conference on "Feminism and Classics: Framing the Research Agenda" was held at Princeton University on November 7-10, 1996; the coorganizers were Janet M. Martin (Princeton University) and Judith P. Hallett (University of Maryland). This conference is the second in a series of more-or-less triennial meetings devoted to feminist research in various areas of classical studies. The first of these conferences (...) ("Feminism and Classics I") was held at the University of Cincinnati in 1992 and was codirected by Kathryn J. Gutzwiller and Ann N. Michelini (both of the University of Cincinnati; for a review of this conference see Clara Hardy and Kirk Ormand, BMCR 4.2 [1993] 135-41).The goals of the Princeton conference were several:mdash To address the evidential deficiencies of the traditional classical literary canon-by examining new kinds of sources and evidence, particularly nonliterary texts and material culture; and by giving increased attention to the ancient Near East and Africa (especially Egypt) as well as to post-classical Greek and Latin texts;mdash To address the methodological inadequacies of traditional historical and philological approaches-by applying the new literary and textual criticism and theory to the traditional classical literary canon as well as to nonliterary and postclassical texts; by adopting comparative approaches to the study of ancient sexuality and gender; and by considering women (in addition to men) as agents in the transmission of the classical tradition;mdash To clarify, illuminate, and evaluate the relations between classical scholarship and the politics of social change-by defining the actual and potential relations among feminist studies, gender studies, and women's studies, and the relation of classical studies to each; by examining the variety of relations that feminist and other scholarship can have to the politics of social change; and by addressing the role of theory in feminist scholarship in classics.The conference was divided into four plenary sessions, each one devoted to a core area of feminist scholarly research in classics: The Historical Recovery of Ancient Women (Speakers: Shelby Brown, UCLA [End Page 328] and Alan Shapiro, University of Canterbury, New Zealand; Discussants: Barry S. Strauss, Cornell University and Sandra R. Joshel, New England Conservatory of Music); Women and the Classical Tradition (Speakers: Joan M. Ferrante, Columbia University and Shelley P. Haley, Hamilton College; Discussants: Diana Robin, University of New Mexico and Judith P. Hallett, University of Maryland); Feminist Literary Studies and the Construction of Sexuality and Gender in the Ancient World (Speakers: David Konstan, Brown University and Barbara K. Gold, Hamilton College; Discussants: Ellen Oliensis, Yale University and Ruth Webb, Princeton University); Feminism and Classics in the Next Century: Feminist Studies, Gender Studies, Women's Studies (Speakers: Peter W. Rose, Miami University of Ohio and Nancy F. Partner, McGill University; Discussants: Sarah B. Pomeroy, Hunter College and CUNY and Amy Richlin, University of Southern California).In addition to the four plenary sessions, there was a rich variety of discussion and presentation in other formats: opening and closing roundtables (including, in addition to some of the speakers and organizers, Nancy Sorkin Rabinowitz, Hamilton College, Barbara M. McManus, College of New Rochelle, Bella Zweig, University of Arizona, Kathryn J. Gutzwiller, and Ann N. Michelini, both of the University of Cincinnati); the keynote address by Ernestine Friedl, Duke University; and sixteen interactive workshops, which followed up on the topics of the plenary sessions. These covered topics as broad as "Reading Gender in Epigraphical Text and Context" (Susan Guettel Cole), "The Classical World in Twentieth-Century Historical Fiction by Women" (Sheila Murnaghan and Deborah H. Roberts), "Feminist Theory/Queer Theory" (Kirk Ormand and Rabinowitz), "Politics, Pedagogy, and the Future of Gender Studies" (Mary Whitlock Blundell, Jeffrey S. Carnes, and John T. Kirby), and "Feminist Anthropology and Feminist Work in Classics" (Deborah Lyons).The conference was one of several events celebrating the 250th anniversary of Princeton University. In certain respects it carried on the work of the 1917 Princeton conference organized by Dean Andrew Fleming West. Entitled "Value of the Classics," the 1917 conference was also in its own way interdisciplinary, documenting the impact of classics on such fields as medicine, law, economics, sociology, and public... (shrink)

According to grounded cognition, words whose semantics contain sensory-motor features activate sensory-motor simulations, which, in turn, interact with spatial responses to produce grounded congruency effects. Growing evidence shows these congruency effects do not always occur, suggesting instead that the grounded features in a word's meaning do not become active automatically across contexts. Researchers sometimes use this as evidence that concepts are not grounded, further concluding that grounded information is peripheral to the amodal cores of concepts. We first review broad evidence (...) that words do not have conceptual cores, and that even the most salient features in a word's meaning are not activated automatically. Then, in three experiments, we provide further evidence that grounded congruency effects rely dynamically on context, with the central grounded features in a concept becoming active only when the current context makes them salient. Even when grounded features are central to a word's meaning, their activation depends on task conditions. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Bayle’s Anticipation of PopperThomas M. LennonA comprehensive history of skepticism might someday argue, what now perhaps seems prima facie implausible, that Karl Popper (1902–96) was anticipated by Pierre Bayle (1647–1706). Now, pointing out adumbrations, anticipations, or even outright earlier statements of later philosophical views is by itself of only antiquarian interest. Questions of priority may be of importance in the history of science but not in the history of (...) philosophy, in which the exercise must pay off in a better understanding of the connected authors.For example, in a paper called “Locke’s Anticipation of Kripke,” J. L. Mackie drew attention to passages in Locke where the so-called causal theory of reference recently advanced by Kripke and others is at least adumbrated. 1 The so-called traditional theory of reference has it that denotation is fixed by connotation—in the terminology of Locke, reference to a thing requires the idea of that thing. But Mackie discovered that Locke thought it possible, at least under certain circumstances, to refer to the real essence of gold, for example, even though we have no idea whatsoever of that essence. The causal theory is supposed to overthrow the traditional theory precisely in that it systematically allows such reference in ignorance of essence. Mackie’s discovery is ironic, for Locke is the author most often associated with the traditional theory.Mackie himself did nothing with the Locke-Kripke connection, which he seems to have regarded as a curiosity. In fact the anticipation, if startling, seems rather slight and circumscribed considering that, in the passages cited by Mackie, Locke sees such reference only when an instance of gold is present to be referred to. But there is at least this payoff, that the so-called traditional theory of [End Page 695] reference may not be quite traditional. Moreover, it may be, not just Locke, but the whole skeptical tradition that anticipates Kripke. 2There is a close analogy between the Locke-Kripke connection and a connection that will be drawn here between Bayle and Popper. In both cases the seventeenth-century anticipator specifically sets out but clearly rejects a view that is later central to the twentieth-century anticipated. That Kripke should be anticipated by the very author whose “traditional” view is most often held up as a foil to the causal theory obviously involves a certain irony, but any irony in Popper’s being anticipated by such a figure as Bayle will be dispelled by the more systematic connections between them. 3 Here, at the end, some indication of these systematic connections will be sketched, but the main purpose of this paper is only to provide a program for interpreting Bayle. The payoff of Bayle’s anticipation of Popper, then, is an optic that focuses for us this key figure of the early Enlightenment.Some brief indication of the systematic connections between Bayle and Popper will be useful at the outset, lest the main thrust of the paper be missed. After all, the specific anticipation of Popper by Bayle that is likened to Mackie’s Locke-Kripke connection is, like that connection, something of a curiosity—mildly interesting in its own right but without systematic significance by itself—for in both cases, the views are stated only to be rejected. In the case of Bayle and Popper, however, the negative connection leads one to further reflections that yield positive connections—rather as if Locke should be reread as Kripkean in other respects.This result is more interesting in the case of Bayle for two reasons. First, a rereading based on Popper is going to be far more comprehensive and programmatic than would anything based on Kripke. Second, readers of Bayle, far more than those of Locke, are in need of all the interpretive help they can get. Interpretations of Bayle notoriously vary with respect to every one of his views, and do so more widely than for any other figure in his period. Despite his universally acknowledged importance, 4 the literature has taken to referring to the actual views underlying that importance as “the Bayle enigma.” 5 [End Page 696]Here some of that enigma may be dispelled if... (shrink)

Although science supplies medicine's “gold standard,” knowledge exercised in the care of patients is, like moral knowing, a matter of narrative, practical reason. Physicians draw on case narrative to store experience and to apply and qualify the general rules of medical science. Literature aids in this activity by stimulating moral imagination and by requiring its readers to engage in the retrospective construction of a situated, subjective account of events. Narrative truths are provisional, uncertain, derived from narrators whose standpoints are (...) always situated, particular, and uncertain, but open to comparison and reinterpretation. Reading is thus a model for knowing in both morality and clinical medicine. While principles remain essential to bioethics and science must always inform good clinical practice, the tendency to collapse morality into principles and medicine into science impoverishes both practices. Moral knowing is not separable from clinical judgment. While ethics must be open to discussion and interpretation by patients, families, and society, it is nevertheless substantively and epistemologically an inextricable part of a physician's clinical practice. (shrink)

This essay explores the correspondence between cinema and money through an investigation of what I call the 'financialization of the image.' Drawing from the tradition of psychoanalytic film criticism and the cinematic ontology of Gilles Deleuze, it argues that the 'camera-eye' and the 'brain-screen' are distinct modes of organizing cinematic perception in capital. Furthermore, it argues that Gilles Deleuze's understanding of the brain-screen is the most adequate mode of thinking of the organization of subjective vision within control societies and the (...) financialization of life itself. (shrink)

Book reviewed in this article: The Philosophical Assessment of Theology: Essays in Honour of Frederick C. Copleston. Edited by Gerard J. Hughes. Language, Meaning and God: Essays in Honour of Herbert McCabe OP. Edited by Brian Davies. God Matters. By Herbert McCabe. Philosophies of History: A Critical Essay. By Rolf Gruner. The ‘Phaedo’: A Platonic Labyrinth. By Ronna Burger. Lessing's ‘Ugly Ditch’: A Study of Theology and History. By Gordon E. Michalson, Jr. Peirce. By Christopher Hookway. Frege: Tradition and Influence. (...) Edited by Crispin Wright. The Private World. Selections from the Diario Íntimo and Selected Letters 1890–1936. By Miguel de Unamuno, translated by Anthony Kerrigan, Allen Lacy, Martin Nozick. A Third Collection: Papers by Bernard J.F. Lonergan, S.J. Edited by Frederick E. Crowe. Philosophical Papers. By Charles Taylor. 2 vols. Principles of Language and the Mind. By T.P. Waldron. The Principle of Double Effect: A Critical Appraisal of its Traditional Understanding and its Modern Reinterpretation. By L.I. Ugorji. Human Rights: Fact or Fancy By Henry B. Veatch. Enlightenment and Alienation: An Essay towards a Trinitarian Theology. By Colin Gunton. Only Human. By Don Cupitt. The Roots of the Modern Christian Tradition. Edited by E. Rpzanne Elder. ‘Africanische Theologie’: Darstellung und Dialog.. By Heribert Rücker. African Religions in Western Conceptual Schemes. By Emefie Ikenga Metuh. The Destiny of Man: Dagaare Beliefs in Dialogue with Christian Eschatology. By Edward Kuukure. The World in Between: Christian Healing and the Struggle for Spiritual Survival. By E. Milingo. Theology in Africa. By Kwesi A. Dickson. The Future of Anglican Theology. Edited by M. Darrol Bryant. Reconciling. By John Coventry. The Genesis of Faith: The Depth Theology of Abraham Joshua Heschel. By John C. Merkle. Anthropology in Theological Perspective. By Wolfhart Pannenberg. Contemporary Approaches to the Study of Religion. Volume II: The Social Sciences. Edited by Frank Whaling. American Sociology: Worldly Rejections of Religion and Their Directions. By Arthur J. Vidich and Stanford M. Lyman. A Critical Theory of Religion: The Frankfurt School. By Rudolf J. Siebert. The Anthropology of Evil. Edited by David Parkin. The Wealth of Christians. By Redmond Mullin. Biblical Interpretation in Ancient Israel. By Michael Fishbane. Reading the Old Testament: An Introduction. By Lawrence Boadt. Old Testament Theology: Its History and Development. By John H. Hayes and Frederick C. Prussner. God's Conflict with the Dragon and the Sea: Echoes of a Canaanite Myth in the Old Testament. By John Day. Law and Wisdom from Ben Sira to Paul. By Eckhard J. Schnabel. The Order of the Synoptics: Why Three Synoptic Gospels? By Bernard Orchard and Harold Riley. The Making of Mark. By J. Duncan M. Derrett. Argumentation bei Paulus. By Folker Siegert. Christians and the Military: The Early Experience. Edited by Robert J. Daly. Origienes' Eucharistielehre im Streit der Konfessionen; Die Auslegungsgeschichte seit der Reformation. By Lothar Lies. L'église de Cappadoce au IVe siècle d'après la correspondance de Basile de Césarée. By Benpit Gain Cave Monasteries of Byzantine Cappadocia. By Lyn Rodley. Augustine of Hippo, Selected Writings. Translated with an Introduction by Mary T. Clark. Wisdom from St Augustine. By Vernon J. Bourke. A History of Religious Ideas, Vol. 3: From Muhammad to the Age of Reforms. By Mircea Eliade. Les Lectionnaires Copies Annuels: Basse‐Egypte. By Ugo Zanetti. Humanism and Scholasticism in Late Medieval Germany. By James H. Overfield. Wyclif. By Anthony Kenny. The Lady and the Virgin: Image, Attitude and Experience in Twelfth Century France. By Penny Shine Gold. Unquiet Souls: Fourteenth‐Century Saints and Their Religious Milieu. By Richard Kieckhefer. Luther: Theologian for Catholics and Protestants. Edited by George Yule. La Réforme Catholique: Le Combat de Maldonat. By Paul Schmitt. Roman Catholicism in England: From the Elizabethan Settlement to the Second Vatican Council. By Edward Norman. The Life of David Brainerd. Edited by Norman Pettit. Nineteenth Century Religious Thought in the West. Edited by Ninian Smart, John Clayton, Patrick Sherry and Steven T. Katz The Significance of Jesus Christ in Asia. By Hans Staffner. Is the Virgin Mary Appearing at Medjugorje? By René Laurentin and Ljudevit Rupčić. Mary Queen of Peace: Is the Mother of God Appearing in Medjugorje? By Lucy Rooney and Robert Fancy. (shrink)

This chapter contains sections titled: Introduction How to Read Maimonides' Guide of the Perplexed Belief and Articles of Faith The Art of Biblical Exegesis: Harvesting “Apples of Gold” Language and Logic Philosophy and the Art of Demonstration Conclusion: Implications of Maimonides' Views further reading.

For more than six decades, and for thousands of students, Introduction to Logic has been the gold standard in introductory logic texts. In this 15th Edition, Carl Cohen and Victor Rodych update Irving M. Copi's classic text, improving on its many strengths and introducing new and helpful material that will greatly assist both students and instructors.

Gold & Stoljar 's attempt to disentangle the body-mind problem in time for the end of the decade of the brain deserves praise for its diligence and courage in moving onto the treacherous ground of interdisciplinary discourse. In making their point, they should not have stopped half-way: a more clearly defined experimental paradigm seems necessary to solve this exciting and substantial problem.

Despite the ubiquity of bees in Dickinson’s work, most interpreters denigrate her nature poems. But following several recent scholars, I identify Nietzschean/Dionysian overtones in the bee poems and suggest the figure of bees/hive/queen illuminates as feminist key to her corpus. First, (a) the bee’s sting represents martyred death; (b) its gold, immortality; (c) its tongue, the “lesbian phallus”; (d) its wings, poetic power; (e) its buzz, poetic melody, and (f) its organism, a joyful Dionysian Susan (her sister-in-law and love (...) interest) to Emily’s flower. Second, the hive represents her individual poems (with slants/dashes as stingers, wings as hymn meter, honey as rhymes, variant words as exiled bees, and accompanying flowers their Darwinian coevolution with bees), constituting her writing persona as a multi-voiced self-swarm, as organized in the apiary of her letters and fascicles. And third, the queen represents her Western cultural and religious inheritance wherein bees are symbols of the soul, reincarnation, poetic-philosophical vocation, and a Nietzschean, trans-Dionysian naturalist ontology—symbolized by apiarian Artemis. (shrink)

Astonishing changes have occurred to agricultural production systems since WWII. As such, many people tend to date the origins of industrial chemical agricultural to the early 1940s. The origins of industrial chemical agriculture, however, both on and off the field, have a much longer history. Indeed, industrial agriculture’s much discussed chemical dependency—in particular its need for toxic chemicals—and the development of the industries that feed this fix, have a long and diverse past that extend well back into the nineteenth century. (...) In this paper, through the narrative of a late nineteenth century creation story, I go in search of a crucial linchpin in that longer history. I argue that industrial pest control has been imbued with the practices, discourse, materials, and ethics of modern chemical warfare since its inception. Faced with pest-induced collapse, Los Angeles citrus growers and scientists of the USDA and UC Agricultural Extension chemically fixed the citrus pest problem by developing and utilizing the cyanide gas chamber. Cyanide fumigation quickly became the toxic cornerstone of the citrus industry, enabling its intensification and expansion as the pest infection became systemic. By the turn the century, furnished with an economic poison made cheap and weapons-grade due to changes in the world gold mining industry, growers transformed cyanide fumigation into a necessary agricultural input. In chemically overriding an agro-ecological contradiction of capitalist agriculture, growers, scientists, and government officials amalgamated industrially organized agriculture to accelerating and endless chemical warfare. These suddenly necessary agricultural practices signaled a state change in world-ecology and agroindustrial organization, thus, the discovery of effective industrial control for citrus pests was not only a pivotal moment in the history of Southern California but it was also an event that has had world-historical implications. (shrink)

In a recent comment on H.L.A. Hart’s ‘Postscript’ to The Concept of Law, Ronald Dworkin claims that the meaning of legal and political concepts may be understood by analogy to the meaning of natural kind concepts like ‘tiger’, ‘gold’ and ‘water’. This article questions the efficacy of Dworkin’s claims by challenging the use of natural kinds as the basis for a semantic theory of legal and political concepts. Additionally, in matters of value there is no methodological equivalent to the (...) scientific method. Thus, there is little hope of finding hidden essences to explain the meaning of legal and political concepts. Finally, even if there are natural kinds, Dworkin’s arguments for their efficacy in jurisprudence are problematic and unpersuasive. The problem for Dworkin is that his embrace of natural kinds undermines the ‘fit’ side of the fit/justification model of adjudication that lies at the heart of his theory of law. (shrink)

This article investigates several discussions of “chemistry,” understood as an analysts’ category referring to theories and practices dealing with the structure and transformation of matter. By reading these texts (a treatise defending kīmiyāʾ by al-Fārābī, the famous passage from Ibn Sīnā’s Shifāʾ on transmutation, Ibn Taymiyyah’s fatwā against kīmiyāʾ, Michael Psellos’s treatise On Making Gold, and the same author’s Accusation against a sitting Patriarch of Constantinople), the article aims to lay the groundwork for integrating the historiography of Byzantine and (...) Arabic alchemy into a wider western Eurasian intellectual history. (shrink)

The Eurozone’s reaction to the crisis beginning in late 2008 involved not only efforts to mitigate the arbitrarily destructive effects of markets but also vigorous pursuit of policies aimed at austerity and deflation. To explain this paradoxical outcome, I build on Karl Polanyi’s account of a similar deadlock in the 1930s. Polanyi argued that a society-protecting response to malfunctioning markets was limited under the gold standard by the prospect of currency panic, which bankers used to push for austerity, deflationary (...) policies, and labor’s political marginalization. I reconstruct Polanyi’s “governing by panic” theory to explain Eurozone policy during three key episodes of sovereign bond market panic in 2010–12. By threatening to allow financial panics to continue, the European Central Bank promoted policies and institutional changes aimed at austerity and deflation, limiting the protective response. Germany’s Ordoliberalism, and its weight in European affairs, contributed to the credibility of this threat. (shrink)

In a recent paper, Ebbs has given an elegant statement of a notable puzzle that has recurred in the literature since the original publication of Putnam’s “The Meaning of ‘Meaning’.” The puzzle can be formulated, for a certain characteristic case, along the following lines. There are very strong intuitions in support of a thesis that Putnam has explicitly endorsed, namely, the thesis: The extension of the word ‘gold’, as we use it now, is the same as the extension of (...) ‘gold’, as it was used in 1650 (before the rise of molecular chemistry). However, strong convictions about language use and truth conditions also incline us to the view that the extension of a term, as it is used at a time t, is determined by facts about the use of the term in the language at or before t, together with the facts about the various items to which the term prospectively applied. This paper looks at the various issues involved regarding these matters. (shrink)

Britain's abandonment of the Gold Standard in 1931 raised new economic policy problems both for Britain and for the countries of the Empire, who had to decide whether to follow sterling off gold and, if so, whether to peg their currencies to sterling. By exploiting archival material, the author casts fresh light on the debates and financial diplomacy of the period, and provides a fuller understanding of several key issues: the formation of the sterling area, the World Economic (...) Conference of 1933, and American concerns about the price and course of sterling. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Was Jesus a Buddhist?James M. HansonWas Jesus a Buddhist? Certainly he was many things—Jew, prophet, healer, moralist, revolutionary, by his own admission the Messiah, and for most Christians the Son of God and redeemer of their sins. And there is convincing evidence that he was also a Buddhist. The evidence follows two independent lines—the first is historical, and the second is textual. Historical evidence indicates that Jesus was well (...) acquainted with Buddhism. If Jesus did not go to India, then at least India went to Judea and Jesus. The real historical question is not if he studied Buddhism, but where and how much he studied Buddhism, especially during his so-called "lost years."Historical accounts aside, many textual analyses indicate striking similarities between what was said by Jesus and by Buddha and between the prophetic legend of Jesus and ancient Buddhist texts. The conclusion is that, although not identifying himself as a Buddhist for good reasons, Jesus spoke like a Buddhist. The similarities are so striking that, even if no historical evidence existed, we can suspect that Jesus studied Buddhist teachings and that the prophecy and legend of Jesus was derived from Buddhist stories.Historical Evidence of Buddhism in JudeaHistorical evidence indicates that Jesus knew about Buddhism, simply because both he and it were in Judea during the same time. Other evidence, while perhaps apocryphal, indicates that he spent most of his so-called lost years outside Judea, possibly in Kashmir to study Buddhism exclusively.I owe thanks to the barbed but benign comments of my friend, Dale Bengtson.Regarding Buddhism in Judea, Jesus did not live in a pastoral, ethnically isolated place and time. On the contrary, non-Jewish political and cultural influences permeated Judea, which was an important shipping center for trade between India and the West and the military gateway to invade Egypt via land. Both land and sea trade routes had run through Jerusalem for centuries. Overland routes extending to Persia and western India were especially active after Alexander's invasion of western India 360 years earlier; most of the routes, whether connecting to wealthy cities in Egypt or in Greece and Rome, came through Jerusalem, where goods for Greece and Rome were shipped via the Mediterranean Sea. Sea routes from Bombay and the mouth of [End Page 75] the Indus River went through the Persian and Red Gulfs, the distance between the mouths of the Indus and Tigris and Euphrates rivers being only about three hundred miles; much of the trade came up the Gulf of Aquaba and overland up to Jerusalem (actually nearby Jappa) as the shipping point to the Mediterranean.During Jesus' time, Judea was a Roman dominion and most of the trade was Roman. Being the wealthiest empire of the time, Rome sent tons of gold-minted sesterces eastward for goods from India and other places. Most of this trade came over the Mediterranean and through Judea, making Jerusalem a cosmopolitan shipping center. Because of trade alone, Zoroastrianism and Buddhism were well known to the people in Judea. News from other lands was naturally of great interest. Most traders provided detailed accounts of the events of cities and states along their routes, often in the form of eloquent verse. Easterners in Judea were as anxious to hear news as were Jews in Persia or western India.In addition to trade, Zoroastrians and Buddhists settled in northern Arabia, including Judea, which was only two hundred miles from Mesopotamia. The story of Jesus' birth attracting the three Magi priests, if true, demonstrated close ties with Zoroastrians. Settlements occurred especially during Alexander's invasion of the East after 330 BCE. This included Jews who welcomed Alexander's overthrow of Egyptian rule and who joined Alexander's army. Many settled along the invasion route through Persia and what is now Afghanistan and Kashmir/Punjab, a practice encouraged by Alexander to maintain his empire. About 360 years later, Jesus dispatched Thomas, perhaps his closest and most loyal apostle, to practice Christianity in India. The descendants of these Jews continue today to reside in Kashmir or Punjab.Were Buddhists really in Judea, as Jews were in India? In Jesus' time Buddhism was already... (shrink)

This book discusses how rational choice theory grew out of RAND's work for the US Air Force. It concentrates on the work of William J. Riker, Kenneth J. Arrow, James M. Buchanan, Russel Hardin, and John Rawls. It argues that within the context of the US Cold War with its intensive anti-communist and anti-collectivist sentiment, the foundations of capitalist democracy were grounded in the hyper individualist theory of non-cooperative games.

To commemorate 40 years since the founding of the Journal of Business Ethics, the editors in chief of the journal have invited the editors to provide commentaries on the future of business ethics. This essay comprises a selection of commentaries aimed at creating dialogue around the theme Business versus Ethics?. The authors of these commentaries seek to transcend the age-old separation fallacy :409–421, 1994) that juxtaposes business and ethics/society, posing a forced choice or trade off. Providing a contemporary take on (...) the classical question “if it’s legal is it ethical?”, David Hess explores the role of the law in promoting or hindering stakeholder-oriented purpose and governance structure. Jeffrey Harrison encourages scholars to move beyond the presupposition that businesses are either strategic or ethical and explore important questions at the intersection of strategy and ethics. The proposition that business models might be inherently ethical or inherently unethical in their design is developed by Sheila Killian, who examines business systems, their morality, and who they serve. However, the conundrum that entrepreneurs are either lauded for their self-belief and risk-taking, or loathed for their self-belief and risk-taking, is discussed by M. Tina Dacin and Julia Roloff using the metaphor of taboos and totems. These commentaries seek to explore positions that advocate multiplicity and tensions in which business ethics is not either/or but both. (shrink)

There is a long-standing debate in philosophy about whether it is morally permissible to harm one person in order to prevent a greater harm to others and, if not, what is the moral principle underlying the prohibition. Hypothetical moral dilemmas are used in order to probe moral intuitions. Philosophers use them to achieve a reflective equilibrium between intuitions and principles, psychologists to investigate moral decision-making processes. In the dilemmas, the harms that are traded off are almost always deaths. However, the (...) moral principles and psychological processes are supposed to be broader than this, encompassing harms other than death. Further, if the standard pattern of intuitions is preserved in the domain of economic harm, then that would open up the possibility of studying behavior in trolley problems using the tools of experimental economics. We report the results of two studies designed to test whether the standard patterns of intuitions are preserved when the domain and severity of harm are varied. Our findings show that the difference in moral intuitions between bystander and footbridge scenarios is replicated across different domains and levels of physical and non-physical harm, including economic harms. (shrink)

About one third of patients with epilepsy have seizures refractory to the medical treatment. Electrical stimulation mapping is the gold standard for the identification of “eloquent” areas prior to resection of epileptogenic tissue. However, it is time-consuming and may cause undesired side effects. Broadband gamma activity recorded with extraoperative electrocorticography during cognitive tasks may be an alternative to ESM but until now has not proven of definitive clinical value. Considering their role in cognition, the alpha and beta bands could (...) further improve the identification of eloquent cortex. We compared gamma, alpha and beta activity, and their combinations for the identification of eloquent cortical areas defined by ESM. Ten patients with intractable focal epilepsy participated in a delayed-match-to-sample task, where syllable sounds were compared to visually presented letters. We used a generalized linear model approach to find the optimal weighting of each band for predicting ESM-defined categories and estimated the diagnostic ability by calculating the area under the receiver operating characteristic curve. Gamma activity increased more in eloquent than in non-eloquent areas, whereas alpha and beta power decreased more in eloquent areas. Diagnostic ability of each band was close to 0.7 for all bands but depended on multiple factors including the time period of the cognitive task, the location of the electrodes and the patient’s degree of attention to the stimulus. We show that diagnostic ability can be increased by 3–5% by combining gamma and alpha and by 7.5–11% when gamma and beta were combined. We then show how ECoG power modulation from cognitive testing can be used to map the probability of eloquence in individual patients and how this probability map can be used in clinical settings to optimize ESM planning. We conclude that the combination of gamma and beta power modulation during cognitive testing can contribute to the identification of eloquent areas prior to ESM in patients with refractory focal epilepsy. (shrink)

Because of his preoccupation with the formal aspects of music and literature, Theodor W. Adorno is often regarded as the most aesthetically oriented thinker of the Frankfurt School theorists. It is Adorno’s perceived commitment to aestheticism—the study of art for art’s sake and the study of art as a source of sensuous pleasure, rather than as a vehicle for culturally constructed morality or meaning—that many scholars have criticized as hostile to genuine, concrete, substantive political, social, and ethical engagement with the (...) arts. _Adorno and Ethics_—the first issue of _New German Critique_ to be published by Duke University Press—takes issue with Adorno’s critics. These essays reconsider Adorno’s unique brand of aestheticism, revealing a “politics of aestheticism” and exploring the political and ethical dimensions of his writings. One contributor links the ethical turn taken in Adorno criticism with related developments in American poetry and poetics. Another examines Adorno’s aphorism “Gold Assay” for the ways in which it anticipates one of his seminal works, _The Jargon of Authenticity_. Focusing on Auschwitz and the testimony of its survivors, one contributor explores the impact of the Holocaust on modern philosophy and reason, a relationship that he argues Adorno never specified. Another contributor considers the figure of the animal in the writings of Kant, Adorno, and Lévinas, exploring what it might mean to live, as Adorno suggests, as “a good animal.” _Contributors_. J. M. Bernstein, Detlev Claussen, Samir Gandesha, Alexander García Düttmann, Christina Gerhardt, Martin Jay, Robert Kaufman, Michael Marder, Gerhard Richter. (shrink)

В монографии рассматриваются интерпретативные стратегии деконструкции, их историко-философские истоки, а также их значение для постметафизического мышления. Для научных работников, студентов и аспирантов.

Reflective function is defined as an individual’s ability to understand human behavior in terms of underlying mental states including thoughts, feelings, desires, beliefs, and intentions. More specifically, the capacity of parents to keep their child’s mental states in mind is referred to as parental RF. RF has been linked to adult mental health and parental RF to children’s mental health and development. The gold standard measure of RF is the interview-based Reflective Functioning Scale applied to the Parent Development Interview (...) or Adult Attachment Interview, which while well validated, is time-and labor-intensive to administer. Given the increasing need for reliable, valid, and rapid RF assessment in wide-ranging settings, two alternative measures were considered including the Reflective Function Questionnaire and Parental Reflective Function Questionnaire. We determined the convergent validity of these measures in comparison with the PDI-rated RFS. A sample of mothers and fathers was drawn from a sub-study of the ongoing Alberta Pregnancy Outcomes and Nutrition longitudinal cohort when their children were 42–60 months of age. Pearson correlations and multiple linear regression was conducted, followed by splitting the sample to compute Cohen’s kappas measures of agreement. Two subscales of the PRFQ correlated significantly with the gold standard PDI-rated RFS, providing evidence for convergent validity. As a brief multidimensional measure of parental RF, the PRFQ offers an alternative for measurement of RF in large-scale studies of parental development and child health. (shrink)

In examining Ennead VI 4[22], we find Plotinus in conflict with modern, i.e., Cartesian or Kantian, assumptions about the relation of soul and body and the identification of the self with the subject. Curiously, his images and exposition are more in tune with Twentieth Century notions such as wave and field. With these as keys, we are in a position to unlock the subtlety of Plotinus' analysis of the way soul and body are present together, with sensation structured through the (...) body and judgment coming from the soul. The problem of the self concerns not only the unity of the self in terms of body and soul, but also how the self is constituted in relation to other selves, both keeping its individuality and sharing its experiences at the same time. (shrink)

Categorical loudness scaling (CLS) measures provide useful information about an individual’s loudness perception across the dynamic range of hearing. A probability model of CLS categories has previously been described as a multi-category psychometric function (MCPF). In the study, a representative “catalog” of potential listener MCPFs was used in conjunction with maximum-likelihood estimation to derive CLS functions for participants with normal hearing and with hearing loss. The approach of estimating MCPFs for each listener has the potential to improve the accuracy of (...) the CLS measurements, particularly when a relatively low number of data points are available. The present study extends the MCPF approach by using Bayesian inference to select stimulus parameters that are predicted to yield maximum expected information (MEI) during data collection. The accuracy and reliability of the MCPF-MEI approach were compared to the standardized CLS measurement procedure (ISO16832:2006). A non-adaptive, fixed-level, paradigm served as a “gold-standard” for this comparison. The test time required to obtain measurements in the standard procedure is a major barrier to its clinical uptake. Test time was reduced from approximately 15 minutes to approximately 3 minutes with the MEI-adaptive procedure. Results indicated that the test-retest reliability and accuracy of the MCPF-MEI adaptive procedures were similar to the standardized CLS procedure. Computer simulations suggest that the reliability and accuracy of the MEI procedure were limited by intrinsic uncertainty of the listeners represented in the MCPF catalog. In other words, the MCPF provided insufficient predictive power to significantly improve adaptive-tracking efficiency under practical conditions. Concurrent optimization of both the MCPF catalog and the MEI-adaptive procedure have the potential to produce better results. Regardless of the adaptive-tracking method used in the CLS procedure, the MCPF catalog remains clinically useful for enabling maximum-likelihood determination of loudness categories. (shrink)